Variants in the neuronal nitric oxide synthase (nNOS, NOS1) gene are associated with restless legs syndromeīilateral thalamic gray matter changes in patients with restless legs syndrome The LaLiMo Trial: lamotrigine compared with levetiracetam in the initial 26 weeks of monotherapy for focal and generalised epilepsy-an open-label, prospective, randomised controlled multicenter study Comparison with Parkinson's disease and controls Reduced striatal dopamine transporters in idiopathic rapid eye movement sleep behaviour disorder. Haematological aspects of obstructive sleep apnoea A polysomnographic case studyĬlinical features and EEG findings differentiating mesial from neocortical temporal lobe epilepsyĪbsence of nystagmus during REM sleep in patients with vestibular neuritis Hypersomnia associated with bilateral posterior hypothalamic lesion. IPT and IBZM SPECT imaging in subclinical and clinically manifest idiopathic REM sleep behavior disorder, Parkinson's disease, and controlsĪlteration of the striatal dopaminergic system in human narcolepsy Increased muscle activity during rapid eye movement sleep correlates with decrease of striatal presynaptic dopamine transporters. Treatment of idiopathic restless legs syndrome (RLS) with slow-release valproic acid compared with slow-release levodopa/benserazid Heart rate increase in otherwise subclinical seizures is different in temporal versus extratemporal seizure onset: support for temporal lobe autonomic influence. Patient complains about sleep disorders: place "restless legs" therein Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions Variants in the neuronal nitric oxide synthase (nNOS, NOS1) gene are associated with restless legs syndrome. One year open-label safety and efficacy trial with rotigotine transdermal patch in moderate to severe idiopathic restless legs syndromeĮfficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trial. ![]() Pathogenesis, assessment, and implications for treatment Long-term safety and efficacy of rotigotine transdermal patch for moderate-to-severe idiopathic restless legs syndrome: a 5-year open-label extension study.ĭepression in restless legs syndrome. The LaLiMo Trial: lamotrigine compared with levetiracetam in the initial 26 weeks of monotherapy for focal and generalised epilepsy-an open-label, prospective, randomised controlled multicenter study. Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis. Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. Patient with diabetes complains about increasing dizziness while walking
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